Drug delivery

Development of drug / siRNA delivery systems

 

Key publication 

 

 

 

 J.B. Lee, J. Hong, D. K. Bonner, Z. Poon, P. Hammond, Self-assembled RNA interference microsponges for efficient siRNA delivery,

Nature materials, 11, 316-322 (2012) 


 

Related articles 

 

Hyejin Kim, Jaepil Jeong, Dajeong Kim, Gijung Kwak, Sun Hwa Kim, Jong Bum Lee, Bubbled RNA-based Cargo for Boosting RNA Interference 

Advanced Science, 1600523 (2017) 


Jong Seong Ha*, Jaesung Lee*, Jaepil Jeong, Hyejin Kim, Juyoung Byun, Sang Ah Kim, Hak Suk Chung, Jong Bum Lee, Dae-Ro Ahn, Poly-sgRNA/siRNA Poly-Ribonucleoprotein Nanoparticles for Targeted Gene Disruption (*co first author) 

Journal of Controlled Release, 250 (2017) 


Yongkuk Park, Hyejin Kim, Jong Bum Lee, Self-assembled DNA-Guided RNA Nanovector via Step-wise Dual Enzyme Polymerization (SDEP) for Carrier-free siRNA Delivery

ACS Biomater. Sci. Eng., 2,616–624 (2016)

 

H. Kim, Y. Park, J. B. Lee, Self-assembled Messenger RNA Nanoparticles (mRNA-NPs) for Efficient Gene Expression

Scientific reports, 5 (2015)

 

D. Han, Y. Park, H. Nam, J. B. Lee, Enzymatic size control of RNA Particles with complementary rolling circle transcription (cRCT) for efficient siRNA production

Chemical communications, 7 (2014)

 

J.B. Lee, J. Hong, D. K. Bonner, Z. Poon, P. Hammond, Self-assembled RNA interference microsponges for efficient siRNA delivery, 

Nature materials, 11, 316-322 (2012) 

 

 

 

Research groups 

 

 

 

 

 

Hyejin Kim

Jaesung Lee